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PTTG1 抗体

PTTG1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7264333
发货至: 中国
  • 抗原 See all PTTG1 抗体
    PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))
    适用
    • 46
    • 11
    • 10
    • 1
    人, 小鼠, 大鼠
    宿主
    • 35
    • 11
    • 1
    克隆类型
    • 29
    • 18
    多克隆
    标记
    • 29
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This PTTG1 antibody is un-conjugated
    应用范围
    • 22
    • 18
    • 11
    • 9
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human PTTG1 (NP_001269311.1).
    亚型
    IgG
    Top Product
    Discover our top product PTTG1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:100-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    PTTG1 (Pituitary Tumor-Transforming 1 (PTTG1))
    别名
    PTTG1 (PTTG1 产品)
    别名
    EAP1 antibody, HPTTG antibody, PTTG antibody, TUTR1 antibody, PTTG1 antibody, securin antibody, AW555095 antibody, C87862 antibody, Pttg antibody, Pttg3 antibody, Securin antibody, Protein Cut2 antibody, pituitary tumor-transforming 1 antibody, pituitary tumor-transforming gene 1 antibody, securin, sister chromatid separation inhibitor antibody, PTTG1 antibody, Pttg1 antibody, cut2 antibody
    背景
    The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC. The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression. It also contains a destruction box (D box) that is required for its degradation by the APC. The acidic C-terminal region of the encoded protein can act as a transactivation domain. The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus. Three transcript variants encoding the same protein have been found for this gene.
    分子量

    Observed_MW: 24 kDa

    Calculated_MW: 22 kDa

    基因ID
    9232
    UniProt
    O95997
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