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HBEGF 抗体 (AA 51-150) (Biotin)

Cited in 1 publication. This anti-HBEGF antibody is a 兔 多克隆 antibody detecting HBEGF in ELISA 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN701052
发货至: 中国
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Quick Overview for HBEGF 抗体 (AA 51-150) (Biotin) (ABIN701052)

抗原

See all HBEGF 抗体
HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

适用

  • 86
  • 25
  • 25
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 72
  • 15
  • 4
  • 1

克隆类型

  • 67
  • 22
  • 2
多克隆

标记

  • 41
  • 8
  • 7
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This HBEGF antibody is conjugated to Biotin

应用范围

  • 37
  • 27
  • 26
  • 18
  • 13
  • 12
  • 10
  • 9
  • 8
  • 6
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 15
    • 14
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 51-150

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human HB-EGF/DTSF

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • Nawaz, Aminuddin, Kado, Takikawa, Yamamoto, Tsuneyama, Igarashi, Ikutani, Nishida, Nagai, Takatsu, Imura, Sasahara, Okazaki, Ueki, Okamura, Tokuyama, Ando, Matsumoto, Mori, Nakagawa, Kobayashi, Saeki et al.: "CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors. ..." in: Nature communications, Vol. 8, Issue 1, pp. 286, (2018) (PubMed).

  • 抗原

    HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

    别名

    HB-EGF

    背景

    Synonyms: DTR, DTS, DTSF, HEGFL, Proheparin-binding EGF-like growth factor, HBEGF

    Background: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

    基因ID

    1839

    UniProt

    Q99075

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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