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TDG 抗体

This 兔 多克隆 anti-TDG antibody specifically detects TDG in IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7256880
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TDG 抗体 (ABIN7256880)

抗原

See all TDG 抗体
TDG (Thymine-DNA Glycosylase (TDG))

适用

  • 51
  • 19
  • 11
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 39
  • 12

克隆类型

  • 42
  • 10
多克隆

标记

  • 45
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TDG antibody is un-conjugated

应用范围

  • 41
  • 15
  • 12
  • 9
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
Immunofluorescence (IF)
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Recombinant fusion protein of human TDG (NP_003202.3).

    亚型

    IgG
  • 应用备注

    IF 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    TDG (Thymine-DNA Glycosylase (TDG))

    别名

    TDG

    背景

    The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12.

    基因ID

    6996

    UniProt

    Q13569

    途径

    DNA Damage Repair, Chromatin Binding
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