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Leptin Receptor 抗体

LEPR 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7254277
发货至: 中国
  • 抗原 See all Leptin Receptor (LEPR) 抗体
    Leptin Receptor (LEPR)
    适用
    • 114
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    宿主
    • 116
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    克隆类型
    • 113
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    多克隆
    标记
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    This Leptin Receptor antibody is un-conjugated
    应用范围
    • 87
    • 46
    • 36
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Synthetic peptide of human LEPR
    亚型
    IgG
    Top Product
    Discover our top product LEPR Primary Antibody
  • 应用备注
    WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.84 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    Leptin Receptor (LEPR)
    别名
    LEPR (LEPR 产品)
    别名
    CD295 antibody, LEP-R antibody, LEPRD antibody, OB-R antibody, OBR antibody, obr antibody, cd295 antibody, ob-rb antibody, Fa antibody, LEPROT antibody, Leprb antibody, Modb1 antibody, OB-RGRP antibody, Obr antibody, db antibody, diabetes antibody, obese-like antibody, obl antibody, ObRb antibody, Ob-R antibody, Ob-RM antibody, lepr antibody, leptin receptor antibody, leptin receptor S homeolog antibody, LEPR antibody, lepr antibody, Lepr antibody, lepr.S antibody
    背景
    The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).
    分子量

    Observed_MW: Refer to figures

    Calculated_MW: 133 kDa

    UniProt
    P48357
    途径
    JAK/STAT Signaling, AMPK Signaling, Feeding Behaviour
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