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- 抗原 See all C1orf114 (CCDC181) 抗体
- C1orf114 (CCDC181) (Coiled-Coil Domain Containing 181 (CCDC181))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This C1orf114 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Fusion protein of human CCDC181
- 亚型
- IgG
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anti-Coiled-Coil Domain Containing 181 (CCDC181) (AA 91-280) antibody
CCDC181 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IHC 1:40-1:200, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.8 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- C1orf114 (CCDC181) (Coiled-Coil Domain Containing 181 (CCDC181))
- 别名
- CCDC181 (CCDC181 产品)
- 别名
- C1orf114 antibody, RP1-206D15.2 antibody, 4930455F23Rik antibody, AI427889 antibody, RGD1309708 antibody, coiled-coil domain containing 181 antibody, CCDC181 antibody, Ccdc181 antibody
- 背景
- CCDC181, also known as C1orf114, chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf114 gene product has been provisionally designated C1orf114 pending further characterization.
- UniProt
- Q5TID7
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