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SPACA3 抗体

SPACA3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7252069
发货至: 中国
  • 抗原 See all SPACA3 抗体
    SPACA3 (Sperm Acrosome Associated Protein 3 (SPACA3))
    适用
    • 17
    • 10
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 17
    克隆类型
    • 17
    多克隆
    标记
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPACA3 antibody is un-conjugated
    应用范围
    • 11
    • 10
    • 8
    • 1
    ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Full length fusion protein
    亚型
    IgG
  • 应用备注
    IHC 1:30-1:150, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.5 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    SPACA3 (Sperm Acrosome Associated Protein 3 (SPACA3))
    别名
    SPACA3 (SPACA3 产品)
    别名
    1700025M08Rik antibody, ALLP17 antibody, CT54 antibody, LYC3 antibody, LYZL3 antibody, SLLP1 antibody, Lyc3 antibody, mSLLP1 antibody, SPRASA antibody, sperm acrosome associated 3 antibody, SPACA3 antibody, Spaca3 antibody
    背景
    SPACA3 (sperm acrosome associated 3), also known as sperm lysozyme-like protein 1, lysozyme-like protein 3, lysozyme-like acrosomal sperm-specific secretory protein ALLP-17, cancer/testis antigen 54 (CT54), LYC3, SPRASA or LYZL3, is a 215 amino acid protein that participates in the fusion and adhesion of sperm and egg plasma membrane during fertilization. Identified as a novel cancer/testis antigen in hematologic malignancies, SPACA3 has the ability to elicit B-cell immune responses in patients with cancer and is considered a potential target for immunotherapy. A member of the glycosyl hydrolase 22 family which is expressed in testis, placenta and epididymis, SPACA3 exists as two alternatively spliced isoforms, SPACA3 isoform 1 is a single-pass type II membrane protein of the sperm acrosome whereas SPACA3 isoform 2 is a secreted protein. Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.
    UniProt
    Q8IXA5
    途径
    Glycosaminoglycan Metabolic Process
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