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PARP1 抗体 (Cleaved-Asp214)

This anti-PARP1 antibody is a 兔 多克隆 antibody detecting PARP1 in WB, ELISA, IF 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN7251022
发货至: 中国

Quick Overview for PARP1 抗体 (Cleaved-Asp214) (ABIN7251022)

抗原

See all PARP1 抗体
PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This PARP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    Cleaved-Asp214

    产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Synthesized peptide derived from the Internal region of human PARP-1

    亚型

    IgG
  • 应用备注

    WB 1:500-2000, IHC 1:50-300, IF 1:50-300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

    别名

    PARP1

    背景

    This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

    分子量

    Observed_MW: 24 kDa

    Calculated_MW: 113 kDa

    UniProt

    P09874

    途径

    Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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