Caspase 1 抗体 (Cleaved-Asp210)
Quick Overview for Caspase 1 抗体 (Cleaved-Asp210) (ABIN7251010)
抗原
See all Caspase 1 (CASP1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Cleaved-Asp210
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- Synthesized peptide derived from the Internal region of human Caspase-1
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亚型
- IgG
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应用备注
- WB 1:500-2000, IHC 1:50-300, IF 1:50-300
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Caspase 1 (CASP1)
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别名
- CASP1
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背景
- Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
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分子量
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Observed_MW: 25 kDa
Calculated_MW: 45 kDa
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UniProt
- P29466
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途径
- Apoptosis, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
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