PAK1 抗体 (pThr212)
Quick Overview for PAK1 抗体 (pThr212) (ABIN7250809)
抗原
See all PAK1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pThr212
-
产品特性
- Phosphorylated antibody
-
纯化方法
- Affinity purification
-
免疫原
- Synthesized peptide derived from human PAKalpha around the phosphorylation site of Thr212
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- PAK1 (P21-Activated Kinase 1 (PAK1))
-
别名
- PAK1
-
背景
- The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.
-
分子量
-
Observed_MW: 65 kDa
Calculated_MW: 61 kDa
-
UniProt
- Q13153
-
途径
- MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Embryonic Body Morphogenesis
抗原
-