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FGFR4 抗体 (pTyr642)

This anti-FGFR4 antibody is a 兔 多克隆 antibody detecting FGFR4 in WB 和 ELISA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN7250791
发货至: 中国

Quick Overview for FGFR4 抗体 (pTyr642) (ABIN7250791)

抗原

See all FGFR4 抗体
FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

适用

  • 88
  • 36
  • 25
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 72
  • 18
  • 2
  • 1

克隆类型

  • 65
  • 25
  • 2
多克隆

标记

  • 50
  • 8
  • 7
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FGFR4 antibody is un-conjugated

应用范围

  • 52
  • 40
  • 24
  • 22
  • 13
  • 13
  • 12
  • 11
  • 7
  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 11
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr642

    产品特性

    Phosphorylated antibody

    纯化方法

    Affinity purification

    免疫原

    Synthesized peptide derived from human FGFR-4 around the phosphorylation site of Tyr642

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, ELISA 1:10000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    FGFR4 (Fibroblast Growth Factor Receptor 4 (FGFR4))

    别名

    FGFR4

    背景

    The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. FGFR4 (Fibroblast Growth Factor Receptor 4) is a Protein Coding gene. Diseases associated with FGFR4 include Prostate Cancer and Neuroma. Among its related pathways are GPCR Pathway and RET signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is FGFR3.

    分子量

    Observed_MW: 90 kDa

    Calculated_MW: 88 kDa

    UniProt

    P22455

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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