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CHEK2 抗体 (pThr68)

This anti-CHEK2 antibody is a 兔 多克隆 antibody detecting CHEK2 in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN7250719
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CHEK2 抗体 (pThr68) (ABIN7250719)

抗原

See all CHEK2 抗体
CHEK2 (Checkpoint Kinase 2 (CHEK2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CHEK2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    pThr68

    产品特性

    Phosphorylated antibody

    纯化方法

    Affinity purification

    免疫原

    Synthesized peptide derived from human Chk2 around the phosphorylation site of Thr68

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:10000-1:20000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    CHEK2 (Checkpoint Kinase 2 (CHEK2))

    别名

    CHEK2

    背景

    Regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on 'Ser-216', preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at 'Thr-18' and 'Ser-20'.

    分子量

    Observed_MW: 61 kDa

    Calculated_MW: 61 kDa

    UniProt

    O96017

    途径

    p53 Pathway, Apoptosis, Cell Division Cycle
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