TBP 抗体
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北京 101111
Quick Overview for TBP 抗体 (ABIN7250434)
抗原
See all TBP 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Monoclonal Antibody
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纯化方法
- Protein A purification
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免疫原
- Recombinant Protein
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亚型
- IgG
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应用备注
- IHC 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TBP (TATA Box Binding Protein (TBP))
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别名
- TBP
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背景
- This gene encodes TBP, the TATA-binding protein. A distinctive feature of TBP is a long string of glutamines in the N-terminus. This region of the protein modulates the DNA binding activity of the C terminus, and modulation of DNA binding affects the rate of transcription complex formation and initiation of transcription. The number of CAG repeats encoding the polyglutamine tract is usually 32-39, and expansion of the number of repeats increases the length of the polyglutamine string and is associated with spinocerebellar ataxia 17, a neurodegenerative disorder classified as a polyglutamine disease.
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UniProt
- P20226
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途径
- WNT signaling
抗原
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