s100a4 抗体
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- 抗原 See all s100a4 (S100A4) 抗体
- s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This s100a4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein corresponding to Mouse S100A4
- 亚型
- IgG
- Top Product
- Discover our top product S100A4 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:300-1:800
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.75 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- s100a4 (S100A4) (S100 Calcium Binding Protein A4 (S100A4))
- 别名
- S100A4 (S100A4 产品)
- 别名
- 18A2 antibody, 42A antibody, CAPL antibody, FSP1 antibody, MTS1 antibody, P9KA antibody, PEL98 antibody, 42a antibody, Capl antibody, FSp1 antibody, Mts1 antibody, PeL98 antibody, metastasin antibody, pk9a antibody, S100A4 antibody, P9ka antibody, RNP9KA antibody, S100 calcium binding protein A4 antibody, S100 calcium-binding protein A4 antibody, S100A4 antibody, S100a4 antibody
- 背景
- S100A4 is a member of the S100 family of calcium-binding proteins. The S100 family members have been involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100A4 is known to localize to and function in the nucleus, cytoplasm of cells and the extracellular space. S100A4 has also been shown to be associated with tumor growth, motility, invasion, metastasis, angiogenesis, apoptosis and chemoresistance. It is a fibroblast-specific protein associated with mesenchymal cell morphology and motility, is expressed during epithelial-mesenchymal transformations (EMT) in vivo. It is an improved marker for lung fibroblasts that could be useful for investigating the pathogenesis of pulmonary fibrosis. Overexpression of S100A4 is correlated with a worse prognosis inpatients with various types of cancer.
- 分子量
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Observed_MW: 12 kDa
Calculated_MW: 12 kDa
- UniProt
- P26447, P07091, P05942
- 途径
- S100 Proteins
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