Cytochrome C 抗体
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北京 101111
Quick Overview for Cytochrome C 抗体 (ABIN7249416)
抗原
See all Cytochrome C (CYCS) 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Polyclonal Antibody
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse Cytochrome c
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:500-1:1000, IF 1:200-1:800
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.5 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- Cytochrome C (CYCS) (Cytochrome C, Somatic (CYCS))
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别名
- CYCS
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背景
- Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation,cytochrome c can be released from mitochondria into cytoplasm,resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition,cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.
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分子量
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Observed_MW: 12 kDa
Calculated_MW: 12 kDa
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UniProt
- P99999, P62898, P62897
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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