CRYM antibody, zgc:158843 antibody, DFNA40 antibody, THBP antibody, crystallin mu antibody, crystallin, mu antibody, Cro/Cl family transcriptional regulator antibody, crystallin mu L homeolog antibody, CRYM antibody, crym antibody, EAMY_RS27495 antibody, crym.L antibody, Crym antibody
背景
Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness.