-
- 抗原 See all Shootin-1 (SHTN1) 抗体
- Shootin-1 (SHTN1)
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- 非结合性
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of human SHTN1
- 亚型
- IgG
- Top Product
- Discover our top product SHTN1 Primary Antibody
-
anti-Shootin-1 (SHTN1) (AA 21-130) antibody
SHTN1 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Shootin-1 (SHTN1) (N-Term) antibodySHTN1 适用: 人, 大鼠, 小鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:100, ELISA 1:5000-1:10000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.78 mg/mL
- 缓冲液
- PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
- 抗原
- Shootin-1 (SHTN1)
- 别名
- SHTN1 (SHTN1 产品)
- 别名
- Kiaa1598 antibody, Shootin1 antibody, mKIAA1598 antibody, shootin 1 antibody, SHTN1 antibody, Shtn1 antibody
- 背景
- Involved in the generation of internal asymmetric signals required for neuronal polarization and neurite outgrowth. Mediates netrin-1-induced F-actin-substrate coupling or 'clutch engagement' within the axon growth cone through activation of CDC42, RAC1 and PAK1-dependent signaling pathway, thereby converting the F-actin retrograde flow into traction forces, concomitantly with filopodium extension and axon outgrowth. Plays a role in cytoskeletal organization by regulating the subcellular localization of phosphoinositide 3-kinase (PI3K) activity at the axonal growth cone. Plays also a role in regenerative neurite outgrowth. In the developing cortex, cooperates with KIF20B to promote both the transition from the multipolar to the bipolar stage and the radial migration of cortical neurons from the ventricular zone toward the superficial layer of the neocortex. Involved in the accumulation of phosphatidylinositol 3,4,5-trisphosphate (PIP3) in the growth cone of primary hippocampal neurons.
- 分子量
-
Observed_MW: Refer to figures
Calculated_MW: 72 kDa
- UniProt
- A0MZ66
-
You are here:
