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IRGC 抗体

IRGC 适用: 人, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7245341
发货至: 中国
  • 抗原 See all IRGC 抗体
    IRGC (Immunity-Related GTPase Family, Cinema (IRGC))
    适用
    • 29
    • 21
    • 6
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    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 29
    克隆类型
    • 29
    多克隆
    标记
    • 10
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This IRGC antibody is un-conjugated
    应用范围
    • 29
    • 14
    • 13
    • 13
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Synthetic peptide of human IRGC
    亚型
    IgG
  • 应用备注
    IHC 1:30-1:150, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.78 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    IRGC (Immunity-Related GTPase Family, Cinema (IRGC))
    别名
    IRGC (IRGC 产品)
    别名
    IFGGE antibody, CINEMA antibody, IRGC1 antibody, Iigp5 antibody, R30953_1 antibody, Ifgge antibody, Irgc1 antibody, RGD1311107 antibody, F630044M05Rik antibody, Gm1102 antibody, Gm474 antibody, Irgc antibody, immunity related GTPase cinema antibody, interferon-inducible GTPase 5-like antibody, immunity-related GTPase family, cinema antibody, immunity-related GTPase family, cinema 1 antibody, IRGC antibody, LOC476445 antibody, Irgc antibody, Irgc1 antibody
    背景
    Immunity-related GTPases (IRG) (also known as p47 GTPases) are a family of GTPase proteins found in vertebrates, which play critical roles in mediating innate resistance to intracellular pathogens. IRG genes have been found in a number of mammals and lower species including mice, rats, zebrafish and humans. Most of the mouse genes contain interferon-stimulated response elements which mediate transcriptional activation by IFNs. In humans, only two IRG genes have been found: human IRGC encodes a full-length IRG protein that, like the mouse homologue, is constitutively expressed in testis, while human IRGM encodes a considerably truncated protein that is constitutively expressed in cultured cells including some macrophage cell lines. As the two human genes IRGC and IRGM are not subject to IFN control, it has been suggested that the host resistance mechanism supported by IRG proteins in the mouse is lacking in humans.
    UniProt
    Q6NXR0
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