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HLA-C 抗体

HLA-C 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7244870
发货至: 中国
  • 抗原 See all HLA-C 抗体
    HLA-C (Major Histocompatibility Complex Class I C (HLA-C))
    适用
    • 60
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 50
    • 10
    克隆类型
    • 51
    • 9
    多克隆
    标记
    • 25
    • 9
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HLA-C antibody is un-conjugated
    应用范围
    • 34
    • 29
    • 11
    • 9
    • 7
    • 5
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Antigen affinity purification
    免疫原
    Synthetic peptide of human HLA-C
    亚型
    IgG
    Top Product
    Discover our top product HLA-C Primary Antibody
  • 应用备注
    IHC 1:25-1:100, ELISA 1:5000-1:10000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.66 mg/mL
    缓冲液
    PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    HLA-C (Major Histocompatibility Complex Class I C (HLA-C))
    别名
    HLA-C (HLA-C 产品)
    别名
    D6S204 antibody, HLA-JY3 antibody, HLC-C antibody, PSORS1 antibody, major histocompatibility complex, class I, C antibody, HLA-C antibody
    背景
    HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Over one hundred HLA-C alleles have been described .
    UniProt
    P10321
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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