STARD5 antibody, MGC131265 antibody, DKFZp469N2125 antibody, 2310058G22Rik antibody, AI607880 antibody, D7Ertd152e antibody, RGD1561783 antibody, StAR related lipid transfer domain containing 5 antibody, StAR related lipid transfer domain containing 5 S homeolog antibody, StAR-related lipid transfer (START) domain containing 5 antibody, StAR-related lipid transfer domain containing 5 antibody, STARD5 antibody, stard5.S antibody, Stard5 antibody
背景
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1, MIM 184756) and by liver X receptors (e.g., LXRA, MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake.