-
- 抗原 See all Lipocalin 2 (LCN2) 抗体
- Lipocalin 2 (LCN2)
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Lipocalin 2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Synthetic peptide of human LCN2
- 亚型
- IgG
- Top Product
- Discover our top product LCN2 Primary Antibody
-
anti-Lipocalin 2 (LCN2) (AA 21-200) antibody
LCN2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 21-200) antibodyLCN2 适用: 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 21-198) antibodyLCN2 适用: 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 101-198) antibodyLCN2 适用: 人 ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 21-198) antibodyLCN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 21-198) antibodyLCN2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 1-100) antibodyLCN2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) (AA 21-198) antibodyLCN2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D14 unconjugated
anti-Lipocalin 2 (LCN2) (AA 1-198) antibodyLCN2 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Lipocalin 2 (LCN2) antibodyLCN2 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1A1B2 unconjugated
-
- 应用备注
- WB 1:1000-1:5000, IHC 1:50-1:200
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 0.6 mg/mL
- 缓冲液
- PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
- 抗原
- Lipocalin 2 (LCN2)
- 别名
- LCN2 (LCN2 产品)
- 别名
- LCN2 antibody, 24p3 antibody, MSFI antibody, NGAL antibody, AW212229 antibody, Sip24 antibody, lipocalin 2 antibody, LCN2 antibody, Lcn2 antibody
- 背景
- Iron-trafficking protein involved in multiple processes such as apoptosis, innate immunity and renal development. Binds iron through association with 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin, and delivers or removes iron from the cell, depending on the context. Iron-bound form (holo-24p3) is internalized following binding to the SLC22A17 (24p3R) receptor, leading to release of iron and subsequent increase of intracellular iron concentration. In contrast, association of the iron-free form (apo-24p3) with the SLC22A17 (24p3R) receptor is followed by association with an intracellular siderophore, iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration. Involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis, while iron-free form decreases intracellular iron levels, inducing expression of the proapoptotic protein BCL2L11/BIM, resulting in apoptosis. Involved in innate immunity, possibly by sequestrating iron, leading to limit bacterial growth.
- 分子量
- 23 kDa
- NCBI登录号
- NP_005555
- UniProt
- P80188
- 途径
- Cellular Response to Molecule of Bacterial Origin, Transition Metal Ion Homeostasis
-
You are here:
