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ADAM10 抗体

ADAM10 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7240415
发货至: 中国
  • 抗原 See all ADAM10 抗体
    ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
    适用
    • 70
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    • 29
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    • 1
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    人, 大鼠, 小鼠
    宿主
    • 56
    • 14
    • 2
    • 1
    克隆类型
    • 49
    • 24
    多克隆
    标记
    • 34
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    • 1
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    • 1
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    This ADAM10 antibody is un-conjugated
    应用范围
    • 45
    • 17
    • 16
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    • 13
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    • 8
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    • 6
    • 6
    • 4
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human ADAM10
    亚型
    IgG
    Top Product
    Discover our top product ADAM10 Primary Antibody
  • 应用备注
    WB 1:200-1:1000, IHC 1:25-1:100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.3 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))
    别名
    CD156c (ADAM10 产品)
    背景
    Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP).
    分子量
    84 kDa
    UniProt
    O14672
    途径
    Notch Signaling, EGFR Signaling Pathway
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