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CHRDL2 抗体

CHRDL2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7238816
发货至: 中国
  • 抗原 See all CHRDL2 抗体
    CHRDL2 (Chordin-Like 2 (CHRDL2))
    适用
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    宿主
    • 28
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    克隆类型
    • 29
    多克隆
    标记
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    This CHRDL2 antibody is un-conjugated
    应用范围
    • 22
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    Western Blotting (WB), ELISA
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Synthetic peptide of human CHRDL2
    亚型
    IgG
    Top Product
    Discover our top product CHRDL2 Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.3 mg/mL
    缓冲液
    PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CHRDL2 (Chordin-Like 2 (CHRDL2))
    别名
    CHRDL2 (CHRDL2 产品)
    别名
    BNF1 antibody, CHL2 antibody, FKSG37 antibody, 1810022C01Rik antibody, Chl2 antibody, chl antibody, si:dkey-11j5.7 antibody, si:dkey-11j5.7-like antibody, chordin like 2 antibody, chordin-like 2 antibody, CHRDL2 antibody, Chrdl2 antibody, chrdl2 antibody
    背景
    CHRDL2 (chordin-related protein 2), also known as BNF1 (breast tumor novel factor 1) or CHL2 (chordin-like 2), is a 429 amino acid protein that belongs to the chordin family of proteins. CHRDL2 contains three VWFC (von Willebrand Factor type C) domains and is predominantly expressed in uterus and moderately expressed in prostate, liver, ovary, heart and testis. Due to alternative splicing events, CHRDL2 exists as five isoforms, namely isoform I, isoform II, isoform VII, isoform VIII and isoform IX. Two of these isoforms are secreted, while the other three localize to the cytoplasm. Functioning as a BMP-binding inhibitor, CHRDL2 directly interacts with BMPs and blocks their binding to BMP receptors, thereby inhibiting BMP activity. In breast, lung and colon tumors, CHRDL2 expression is upregulated, suggesting a possible role in tumorigenesis.
    分子量
    48 kDa
    NCBI登录号
    NP_056239
    UniProt
    Q6WN34
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