SLC30A8 抗体 (N-Term)
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- 抗原 See all SLC30A8 抗体
- SLC30A8 (Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SLC30A8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 特异性
- Two isoforms of SLC30A8 are known to exist, this antibody will detect both isoforms. This SLC30A8 antibody is predicted to not cross-react with other members of the SLC30 protein family.
- 纯化方法
- SLC30A8 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- SLC30A8 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human SLC30A8.
- 亚型
- IgG
- Top Product
- Discover our top product SLC30A8 Primary Antibody
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anti-Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8) (AA 263-369) antibody
SLC30A8 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8) (AA 101-200) antibodySLC30A8 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8) (AA 107-156) antibodySLC30A8 适用: 人, Pig, 马, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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SLC30A8 antibody can be used for Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- SLC30A8 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- SLC30A8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- SLC30A8 (Solute Carrier Family 30 (Zinc Transporter), Member 8 (SLC30A8))
- 别名
- SLC30A8 (SLC30A8 产品)
- 别名
- C820002P14Rik antibody, ZnT-8 antibody, ZnT8 antibody, slc30a3 antibody, znt8 antibody, ZNT8 antibody, E130106K10Rik antibody, Gm212 antibody, wu:fe49g03 antibody, RGD1305098 antibody, solute carrier family 30 member 8 antibody, solute carrier family 30 (zinc transporter), member 8 antibody, solute carrier family 30 (zinc transporter), member 8 L homeolog antibody, solute carrier family 30, member 10 antibody, SLC30A8 antibody, Slc30a8 antibody, slc30a8.L antibody, slc30a8 antibody, Slc30a10 antibody
- 背景
- SLC30A8 Antibody: SLC30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles and is expressed at a high level in the pancreas, particularly in islets of Langerhans, and co-localizes with insulin in the secretory pathway granules of the insulin-secreting INS-1 cells (1). Allelic variants of SLC30A8 have been identified as major genetic risk factors for the development of Type 2 diabetes (2), but no genetic association has been found with Type 1 diabetes (3). SLC30A8 expression in ?-cells was found to be influenced by cytokine expression, particularly IFN-gamma and IL-1beta (4).
- 分子量
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Predicted: 35, 41 kDa
Observed: 35, 41 kDa - 基因ID
- 169026
- NCBI登录号
- NP_776250
- UniProt
- Q8IWU4
- 途径
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Carbohydrate Homeostasis, Transition Metal Ion Homeostasis
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