INPP4B 抗体 (N-Term)
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- 抗原 See all INPP4B 抗体
- INPP4B (Inositol Polyphosphate-4-Phosphatase, Type II, 105kDa (INPP4B))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This INPP4B antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunocytochemistry (ICC)
- 特异性
- INPP4B antibody is human, mouse and rat reactive. At least two isoforms of INPP4B are known to exist, this antibody only detects the longer isoform. INPP4B antibody is predicted to not cross-react with INPP4A.
- 纯化方法
- INPP4B antibody is affinity chromatography purified via peptide column.
- 免疫原
- INPP4B antibody was raised against a 17 amino acid peptide near the amino terminus of human INPP4B. The immunogen is located within the last 50 amino acids of INPP4B.
- 亚型
- IgG
- Top Product
- Discover our top product INPP4B Primary Antibody
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anti-Inositol Polyphosphate-4-Phosphatase, Type II, 105kDa (INPP4B) (AA 1-53) antibody
INPP4B 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3F2 unconjugated
anti-Inositol Polyphosphate-4-Phosphatase, Type II, 105kDa (INPP4B) (AA 367-393) antibodyINPP4B 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22321 unconjugated
anti-Inositol Polyphosphate-4-Phosphatase, Type II, 105kDa (INPP4B) (AA 1-53) antibodyINPP4B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-4-Phosphatase, Type II, 105kDa (INPP4B) (C-Term) antibodyINPP4B 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-4-Phosphatase, Type II, 105kDa (INPP4B) (AA 380-600) antibodyINPP4B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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INPP4B antibody can be used for detection of INPP4B by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL.
Antibody validated: Western Blot in mouse samples and Immunocytochemistry in mouse samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- INPP4B antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- INPP4B antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- 抗原
- INPP4B (Inositol Polyphosphate-4-Phosphatase, Type II, 105kDa (INPP4B))
- 别名
- INPP4B (INPP4B 产品)
- 别名
- E130107I17Rik antibody, inositol polyphosphate-4-phosphatase, type II antibody, inositol polyphosphate-4-phosphatase type II B antibody, Inpp4b antibody, INPP4B antibody
- 背景
- Inositol polyphosphate 4-phosphatase type II (INPP4B) is one of the enzymes involved in phosphatidylinositol signaling pathways. It removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate (1). INPP4B can function as a tumor suppressor by inhibiting PI3K signaling. In human epithelial cells, knockdown of INPP4B expression resulted in enhanced Akt activation, anchorage-independent growth, and enhanced overall motility (2). It is thought INPP4B may also have oncogenic functions as INPP4B-dependent PI3K signaling is mediated by SGK3 in breast cancer cells and expression of INPP4B leads to enhanced SGK3 activation and suppression of AKT phosphorylation (3).
- 分子量
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Predicted: 102 kDa
Observed: 100 kDa - 基因ID
- 8821
- NCBI登录号
- NP_003857
- UniProt
- Q9BS68
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