SLC1A7 antibody is human and mouse reactive. Multiple isoforms of SLC1A7 are known to exist.
纯化方法
SLC1A7 antibody is affinity chromatography purified via peptide column.
免疫原
SLC1A7 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human SLC1A7. The immunogen is located within amino acids 460 - 510 of SLC1A7.
SLC1A7 antibody can be used for detection of SLC1A7 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
SLC1A7 antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
SLC1A7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
抗原
SLC1A7
(Solute Carrier Family 1 (Glutamate Transporter), Member 7 (SLC1A7))
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背景
The solute carrier family 1 member 7 (SLC1A7) protein was initially identified as a glutamate transporter coupled to a chloride conductance that is expressed primarily in the retina (1). More recent evidence indicates that is it widely expressed in peripheral tissues, also (2). Experiments have shown that SLC1A7 functions as a low-affinity/low-capacity glutamate transport, with an anion channel optimized for anion conductance in the negative voltage range (3). In the retina, SLC1A7 co-localizes with the serum and glucocorticoid dependent kinase SGK1, and its cell surface expression and activity is regulated SGK1 and its isoform SGK3 (4).