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ATG4D 抗体 (N-Term)

This anti-ATG4D antibody is a 兔 多克隆 antibody detecting ATG4D in WB, ELISA, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6992097
发货至: 中国

Quick Overview for ATG4D 抗体 (N-Term) (ABIN6992097)

抗原

See all ATG4D 抗体
ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ATG4D antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    N-Term

    特异性

    ATG4D antibody is human, mouse and rat reactive. At least two isoforms of ATG4D are known to exist, this antibody will detect only the larger isoform. ATG4D is predicted to not cross-react with other ATG4 proteins.

    纯化方法

    ATG4D antibody is affinity chromatography purified via peptide column.

    免疫原

    ATG4D antibody was raised against a 17 amino acid peptide near the amino terminus of human ATG4D. The immunogen is located within the first 50 amino acids of ATG4D.

    亚型

    IgG
  • 应用备注

    ATG4D antibody can be used for detection of ATG4D by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    ATG4D antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    ATG4D antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

    别名

    ATG4D

    背景

    Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2). ATG4D, also known as AUTL4, is one of four mammalian orthologs of the yeast ATG4 protein, all four are cysteine proteases (3). ATG4 is required for ATG8 conjugation to phosphatidylethanolamine on autophagosomal membranes. In mammals, each ATG4 homolog shows a selective preference for the ATG8 homologs (4).

    分子量

    Predicted: 52 kDa

    Observed: 49 kDa

    基因ID

    84971

    NCBI登录号

    NP_116274

    UniProt

    Q86TL0

    途径

    Autophagy
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