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NOX1 抗体 (AA 210-260)

The 兔 多克隆 anti-NOX1 antibody is suitable to detect NOX1 in samples from 人. It has been validated for WB, ELISA, IHC (p) 和 IF.
产品编号 ABIN6992042
发货至: 中国
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Quick Overview for NOX1 抗体 (AA 210-260) (ABIN6992042)

抗原

See all NOX1 抗体
NOX1 (NADPH Oxidase 1 (NOX1))

适用

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宿主

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克隆类型

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多克隆

标记

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This NOX1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
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    AA 210-260

    特异性

    NOX1 antibody is human specific.

    纯化方法

    NOX1 antibody is affinity chromatography purified via peptide column.

    免疫原

    NOX1 antibody was raised against a 15 amino acid peptide near the center of human NOX1. The immunogen is located within amino acids 210 - 260 of NOX1.

    亚型

    IgG
  • 应用备注

    NOX1 antibody can be used for detection of NOX1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    NOX1 antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    NOX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    NOX1 (NADPH Oxidase 1 (NOX1))

    别名

    NOX1

    背景

    Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress (1). NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox (1). Three splice variants of NOX1 have been identified, NOH-1L, NOH-1S and NOH-1Lv (2). NOH-1S is a voltage-gated proton channel that participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain (1-3). NOX1 have the potential to be effective treatments for a range of ischemic diseases (4).

    分子量

    Predicted: 62 kDa

    Observed: 64 kDa

    基因ID

    27035

    NCBI登录号

    NP_008983

    UniProt

    Q9Y5S8

    途径

    Regulation of Systemic Arterial Blood Pressure by Hormones, Proton Transport
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