NOX1 抗体 (AA 210-260)
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Quick Overview for NOX1 抗体 (AA 210-260) (ABIN6992042)
抗原
See all NOX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 210-260
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特异性
- NOX1 antibody is human specific.
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纯化方法
- NOX1 antibody is affinity chromatography purified via peptide column.
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免疫原
- NOX1 antibody was raised against a 15 amino acid peptide near the center of human NOX1. The immunogen is located within amino acids 210 - 260 of NOX1.
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亚型
- IgG
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应用备注
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NOX1 antibody can be used for detection of NOX1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- NOX1 antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- NOX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- NOX1 (NADPH Oxidase 1 (NOX1))
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别名
- NOX1
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背景
- Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress (1). NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox (1). Three splice variants of NOX1 have been identified, NOH-1L, NOH-1S and NOH-1Lv (2). NOH-1S is a voltage-gated proton channel that participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain (1-3). NOX1 have the potential to be effective treatments for a range of ischemic diseases (4).
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分子量
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Predicted: 62 kDa
Observed: 64 kDa -
基因ID
- 27035
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NCBI登录号
- NP_008983
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UniProt
- Q9Y5S8
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, Proton Transport
抗原
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