TET2 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for TET2 抗体 (C-Term) (ABIN6991984)
抗原
See all TET2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1550-1600, C-Term
-
特异性
- TET2 antibody is human and mouse reactive. At least two isoforms of TET2 are known to exist, this antibody will detect the larger isoforms. This antibody is predicted to not cross-react with TET1 and TET3.
-
纯化方法
- TET2 antibody is affinity chromatography purified via peptide column.
-
免疫原
- TET2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human TET2. The immunogen is located within amino acids 1550 - 1600 of TET2.
-
亚型
- IgG
-
-
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 1833-2002) antibody
TET2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) antibodyTET2 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5H8C7 unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) antibodyTET2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) antibodyTET2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5H8B3 unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 1833-2002) antibodyTET2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (Internal Region) antibodyVerified TET2 适用: 人 ELISA, IHC, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 1-300) antibodyTET2 适用: 人 WB, IP 宿主: 小鼠 Monoclonal 21F11 unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 528-554), (N-Term) antibodyTET2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB37907 unconjugated
anti-Tet Methylcytosine Dioxygenase 2 (TET2) (AA 528-554) antibodyTET2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
TET2 antibody can be used for detection of TET2 by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- TET2 Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- TET2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
-
-
- TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))
-
别名
- TET2
-
背景
- TET2, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. It is a candidate tumor suppressor gene reported to be mutated in approximately 14 % of patients with JAK2V617F-positive myeloproliferative neoplasms (1), and can be mutated in other hematopoietic disorders such as myelodysplastic syndromes, acute myeloid leukemia, and chronic myelomonocytic leukemia (2). Analysis of the TET2 and JAK2 mutations in these neoplasms suggests that mutations in TET2 do not represent a predisposition for acquiring mutations in JAK2.
-
分子量
-
Predicted: 220 kDa
Observed: 220 kDa -
基因ID
- 54790
-
NCBI登录号
- NP_001120680
-
UniProt
- Q6N021
-
途径
- Warburg Effect
抗原
-
