APPBP2 antibody is human, mouse and rat reactive. At least two isoforms of APPBP2 are known to exist, this antibody will detect both isoforms.
纯化方法
APPBP2 antibody is affinity chromatography purified via peptide column.
免疫原
APPBP2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human APPBP2. The immunogen is located within the last 50 amino acids of APPBP2.
APPBP2
适用: 人
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
Alexa Fluor 350
应用备注
APPBP2 antibody can be used for detection of APPBP2 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
APPBP2 antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
APPBP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
抗原
APPBP2
(Amyloid beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2 (APPBP2))
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背景
The amyloid beta precursor protein (cytoplasmic tail) binding protein 2 (APPBP2), also known as PAT1, interacts with microtubules and is functionally associated with beta-amyloid precursor protein transport and/or processing (1). The beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease (2). APPBP2 has been found to be highly expressed in breast cancer (3).