Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
特异性
At least two isoforms of SAMSN are known to exist.
纯化方法
SAMSN Antibody is affinity chromatography purified via peptide column.
免疫原
Rabbit polyclonal SAMSN antibody was raised against an 18 amino acid peptide near the carboxy terminus of human SAMSN. The immunogen is located within the last 50 amino acids of SAMSN.
SAMSN antibody can be used for detection of SAMSN by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
SAMSN Antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
SAMSN antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
HACS1 antibody, NASH1 antibody, SASH2 antibody, SH3D6B antibody, SLy2 antibody, 4930571B16Rik antibody, 930571B16Rik antibody, Hacs1 antibody, Nash antibody, samsn1 antibody, wu:fa92h05 antibody, wu:fq83f12 antibody, SAMSN1 antibody, zgc:103427 antibody, SAM domain, SH3 domain and nuclear localization signals 1 antibody, SAM domain, SH3 domain and nuclear localization signals, 1 antibody, SAM domain, SH3 domain and nuclear localisation signals 1a antibody, SAM domain, SH3 domain and nuclear localisation signals 1b antibody, SAMSN1 antibody, Samsn1 antibody, samsn1a antibody, samsn1b antibody
背景
SAMSN Antibody: SAMSN (HACS1) is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains. It encodes a 441 amino acid protein that is differentially expressed in hematopoietic cells and malignancies including myeloid leukemia, lymphoma, and myeloma. SAMSN has restricted expression in human tissues. It has been shown to be up-regulated by B cell activation signals and is a participant in B cell activation and differentiation. SAMSN is an immunoinhibitory adaptor that might be a useful target for immune suppression therapy.