SPINK7/ECRG2 抗体 (C-Term)
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- 抗原 See all SPINK7/ECRG2 (SPINK7) 抗体
- SPINK7/ECRG2 (SPINK7) (Serine Peptidase Inhibitor, Kazal Type 7 (SPINK7))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
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小鸡
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克隆类型
- 多克隆
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标记
- This SPINK7/ECRG2 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- ECRG2 antibody is predicted to not cross-react with other ECRG family members
- 纯化方法
- ECRG2 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- ECRG2 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human ECRG2. The immunogen is located within the last 50 amino acids of ECRG2.
- 亚型
- IgY
- Top Product
- Discover our top product SPINK7 Primary Antibody
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anti-Serine Peptidase Inhibitor, Kazal Type 7 (SPINK7) (AA 51-85) antibody
SPINK7 适用: 人, 小鼠 ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Serine Peptidase Inhibitor, Kazal Type 7 (SPINK7) antibodySPINK7 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Serine Peptidase Inhibitor, Kazal Type 7 (SPINK7) (C-Term) antibodySPINK7 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 小鸡 Polyclonal unconjugated
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- 应用备注
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ECRG2 antibody can be used for detection of ECRG2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in mouse samples and Immunohistochemistry in rat samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- ECRG2 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- ECRG2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- SPINK7/ECRG2 (SPINK7) (Serine Peptidase Inhibitor, Kazal Type 7 (SPINK7))
- 别名
- ECRG2 (SPINK7 产品)
- 别名
- Ecg2 antibody, Ecrg2 antibody, OM antibody, ECG2 antibody, ECRG2 antibody, EG408198 antibody, serine peptidase inhibitor, Kazal type 7 antibody, serine peptidase inhibitor, Kazal type 7 (putative) antibody, Spink7 antibody, SPIK7 antibody, SPINK7 antibody
- 背景
- ECRG2 Antibody: The esophageal cancer-susceptibility gene 2 (ECRG2), also known as SPINK7, is a novel tumor suppressor gene identified from the human esophagus. It interacts directly with metallothionein 2A and urokinase-type plasminogen activator (uPA), and downregulates the activity of uPA, leading to reduced cancer cell migration, invasion and metastasis. ECRG2 forms a complex with uPA and its receptor uPAR, modifying the dynamic association of uPAR with beta1 integrins and disrupting the Src/MAP kinase pathway that normally stimulates cell migration and invasion. ECRG2 may thus represent a novel therapeutic target for cancer.
- 分子量
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Predicted: 9 kDa
Observed: 14 kDa - 基因ID
- 84651
- UniProt
- P58062
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