NSRP1
(Nuclear Speckle Splicing Regulatory Protein 1 (NSRP1))
抗原表位
AA 430-480, C-Term
适用
人, 小鼠, 大鼠
宿主
小鸡
克隆类型
多克隆
标记
This NSRP1 antibody is un-conjugated
应用范围
Western Blotting (WB), ELISA, Immunofluorescence (IF)
特异性
At least three isoforms are known to exist, this antibody will detect all three.
纯化方法
CCDC55 Antibody is affinity chromatography purified via peptide column.
免疫原
CCDC55 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human CCDC55. The immunogen is located within amino acids 430 - 480 of CCDC55.
CCDC55 antibody can be used for detection of CCDC55 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunofluorescence starting at 20 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
CCDC55 Antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
CCDC55 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原
NSRP1
(Nuclear Speckle Splicing Regulatory Protein 1 (NSRP1))
CCDC55 Antibody: CCDC55, also known as Nuclear speckle-related protein 70 (NSrp70), was initially identified by the NIH Mammalian Gene Collection. Nuclear speckles are known to be the storage sites of mRNA splicing regulators. CCDC55 has been suggested to modulate alternative pre-mRNA splicing in vivo. It co-localizes and physically interacts with the SR proteins SC35 and ASF/SF2, essential splicing factors which are required for constitutive splicing and can regulate alternative mRNA splicing. Loss of CCDC55 in mice leads to early embryonic lethality highlights the importance of the functional role of CCDC55.