Survivin 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for Survivin 抗体 (C-Term) (ABIN6991530)
抗原
See all Survivin (BIRC5) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
纯化方法
- Survivin Antibody is affinity chromatography purified via peptide column.
-
免疫原
- Anti-Survivin antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human Survivin. The immunogen is located within the last 50 amino acids of Survivin.
-
亚型
- IgG
-
-
-
-
应用备注
-
WB: 1-5 μ,g/mL, ICC: 10 μ,g/mL, IF: 10 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples, Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Survivin Antibody is supplied in PBS containing 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C,4 °C
-
储存方法
- Survivin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
-
- Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))
-
别名
- Survivin
-
背景
- Survivin Antibody: Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel IAP protein was recently identified and designated survivin, apoptosis inhibitor 4 (API4), and TIAP. Survivin/TIAP interacted with the processed form of caspase-3 and inhibited its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas.
-
分子量
-
Predicted: 17kD
Observed: 17 kD kDa -
基因ID
- 332
-
NCBI登录号
- NP_001159
-
UniProt
- O15392
-
途径
- Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
抗原
-