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ATP2C1 抗体 (C-Term)

ATP2C1 适用: 人, 小鼠 ELISA, WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991521
发货至: 中国
  • 抗原 See all ATP2C1 抗体
    ATP2C1 (ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1))
    抗原表位
    • 9
    • 8
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    C-Term
    适用
    • 40
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 35
    • 5
    克隆类型
    • 37
    • 3
    多克隆
    标记
    • 20
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    This ATP2C1 antibody is un-conjugated
    应用范围
    • 27
    • 20
    • 7
    • 6
    • 2
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    At least four isoforms of ATP2C1 are known to exist, this antibody will recognize only the three longest isoforms. ATP2C1 antibody will not cross-react with ATP2C2.
    纯化方法
    ATP2C1 Antibody is affinity chromatography purified via peptide column.
    免疫原
    ATP2C1 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human ATP2C1. The immunogen is located within the last 50 amino acids of ATP2C1.
    亚型
    IgG
    Top Product
    Discover our top product ATP2C1 Primary Antibody
  • 应用备注
    ATP2C1 antibody can be used for detection of ATP2C1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    ATP2C1 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    ATP2C1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    ATP2C1 (ATPase, Ca++ Transporting, Type 2C, Member 1 (ATP2C1))
    别名
    ATP2C1 (ATP2C1 产品)
    别名
    ATP2C1 antibody, ATP2C1A antibody, BCPM antibody, HHD antibody, PMR1 antibody, SPCA1 antibody, hSPCA1 antibody, Spca1 antibody, si:dkey-11p23.6 antibody, SPCA antibody, 1700121J11Rik antibody, AW061228 antibody, D930003G21Rik antibody, pmr1 antibody, ATPase secretory pathway Ca2+ transporting 1 antibody, ATPase, Ca++ transporting, type 2C, member 1 antibody, ATPase, Ca++-sequestering antibody, ATP2C1 antibody, atp2c1 antibody, Atp2c1 antibody
    背景
    ATP2C1 Antibody: ATP2C1, also known as secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1, belongs to the family of P-type cation transport ATPases. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium from the cytosol to the Golgi lumen. Defects in this gene cause Hailey-Hailey disease, an autosomal dominant disorder characterized by persistent blisters and erosions of the skin. Unlike the related protein ATP2C2, ATP2C1 is ubiquitously expressed and displays a lower maximal turnover rate for overall Ca2+-ATPase reaction and a higher apparent affinity for cytosolic Ca2+ activation of phosphorylation. Recent evidence suggests that ATP2C1 is a key regulator of insulin-like growth factor receptor (IGF1R) processing in tumor progression in basal breast cancers.
    基因ID
    27032
    NCBI登录号
    NP_001001486
    UniProt
    P98194
    途径
    Transition Metal Ion Homeostasis, Ribonucleoside Biosynthetic Process
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