ZMYM2 抗体 (N-Term)
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- 抗原 See all ZMYM2 抗体
- ZMYM2 (Zinc Finger, MYM-Type 2 (ZMYM2))
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抗原表位
- AA 120-170, N-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZMYM2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- At least two isoforms of ZMYM2 are known to exist, this antibody will detect only the longest isoform. ZMYM2 antibody is predicted to not cross-react with other ZMYM protein family members.
- 纯化方法
- ZMYM2 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- ZMYM2 antibody was raised against a 17 amino acid peptide near the amino terminus of human ZMYM2. The immunogen is located within amino acids 120 - 170 of ZMYM2.
- 亚型
- IgG
- Top Product
- Discover our top product ZMYM2 Primary Antibody
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anti-Zinc Finger, MYM-Type 2 (ZMYM2) (Center) antibody
ZMYM2 适用: 人, 小鼠 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, MYM-Type 2 (ZMYM2) (AA 1051-1150) antibodyZMYM2 适用: 人, 大鼠 IHC (p), IF (cc), IF (p), ELISA, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, MYM-Type 2 (ZMYM2) (C-Term) antibodyZMYM2 适用: 人 WB, IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, MYM-Type 2 (ZMYM2) (C-Term) antibodyZMYM2 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, MYM-Type 2 (ZMYM2) (AA 1327-1377) antibodyZMYM2 适用: 人, 大鼠, 小鼠, Cow, 犬, 豚鼠, 兔 WB, IHC (p), IP, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, MYM-Type 2 (ZMYM2) (AA 1250-1300) antibodyZMYM2 适用: 人, 大鼠, 小鼠, Cow, 犬, 小鸡, 猴, Orang-Utan WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ZMYM2 antibody can be used for detection of ZMYM2 by Western blot at 0. 125 - 0.25 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- ZMYM2 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- ZMYM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- ZMYM2 (Zinc Finger, MYM-Type 2 (ZMYM2))
- 别名
- ZMYM2 (ZMYM2 产品)
- 别名
- ZMYM2 antibody, ZNF198 antibody, fc07a10 antibody, wu:fc07a10 antibody, si:dkey-51d17.6 antibody, fim antibody, mym antibody, ramp antibody, scll antibody, zfp198 antibody, znf198 antibody, MGC83724 antibody, FIM antibody, MYM antibody, RAMP antibody, SCLL antibody, 5830413P05Rik antibody, Zfp198 antibody, Znf198 antibody, zinc finger MYM-type containing 2 antibody, zinc finger, MYM-type 2 antibody, zinc finger MYM-type containing 2 L homeolog antibody, ZMYM2 antibody, zmym2 antibody, zmym2.L antibody, Zmym2 antibody
- 背景
- Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression (1). The protein folding and the DNA binding ability are governed by the coordination of a zinc ion (1-3). As a member of the MYM (myeloproliferative and mental retardation) gene family, ZMYM2 has been shown to associate with and stabilize the LSD1-CoREST-HDAC1 (LCH) complex of chromatin through its MYM-type zinc fingers, thereby enhancing the transcriptional repression of several genes (4). Translocation of this gene with the fibroblast growth factor receptor-1 gene (FGFR1) results in a fusion gene, which may be a cause of stem cell leukemia lymphoma syndrome (SCLL) (5).
- 基因ID
- 7750
- UniProt
- Q9UBW7
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