ZC3H12A 抗体 (AA 330-380)
-
- 抗原 See all ZC3H12A 抗体
- ZC3H12A (Zinc Finger CCCH-Type Containing 12A (ZC3H12A))
-
抗原表位
- AA 330-380
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ZC3H12A antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 特异性
- This ZC3H12A antibody is predicted to have no cross-reactivity to other members of the ZC3H12 protein family.
- 纯化方法
- ZC3H12A Antibody is affinity chromatography purified via peptide column.
- 免疫原
- ZC3H12A antibody was raised against a 17 amino acid synthetic peptide near the center of human ZC3H12A. The immunogen is located within amino acids 330 - 380 of ZC3H12A.
- 亚型
- IgG
- Top Product
- Discover our top product ZC3H12A Primary Antibody
-
anti-Zinc Finger CCCH-Type Containing 12A (ZC3H12A) antibody
KO Validated ZC3H12A 适用: 人 WB, IHC, FACS, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger CCCH-Type Containing 12A (ZC3H12A) (AA 331-358) antibodyZC3H12A 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger CCCH-Type Containing 12A (ZC3H12A) (AA 331-358), (Middle Region) antibodyZC3H12A 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger CCCH-Type Containing 12A (ZC3H12A) (AA 1-260) antibodyZC3H12A 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger CCCH-Type Containing 12A (ZC3H12A) (AA 320-369) antibodyZC3H12A 适用: 人, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger CCCH-Type Containing 12A (ZC3H12A) (AA 1-140) antibodyZC3H12A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
ZC3H12A antibody can be used for detection of ZC3H12A by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- ZC3H12A Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- ZC3H12A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
- 抗原
- ZC3H12A (Zinc Finger CCCH-Type Containing 12A (ZC3H12A))
- 别名
- ZC3H12A (ZC3H12A 产品)
- 别名
- CGA antibody, MCPIP antibody, MCPIP1 antibody, RP3-423B22.1 antibody, dJ423B22.1 antibody, BC036563 antibody, Mcpip1 antibody, RGD1306776 antibody, chromogranin A antibody, zinc finger CCCH-type containing 12A antibody, zinc finger CCCH type containing 12A antibody, CHGA antibody, ZC3H12A antibody, Zc3h12a antibody
- 背景
- ZC3H12A Antibody: ZC3H12A, also known as MCPIP, is an essential member of a family of novel CCCH-zinc finger proteins that regulate macrophage activation and may be involved in host immunity and inflammatory diseases. ZC3H12A has RNase activity that prevents some immune disorders by directly affecting the mRNA stability of interleukins such as IL-6 and IL12p40. Mice lacking the ZC3H12A gene suffered from severe anemia, and most dies within 12 weeks. Overexpression of ZC3H12A causes ER stress and induces a number of genes involved in apoptosis and autophagy, including JNK, PUMA, and beclin-1 in cardiac myoblasts, leading to cell death. ZC3H12A can also induce adipogenesis in 3T3-L1 pre-adipocytes in the absence of PPAPgamma, demonstrating the complex roles ZC3H12A plays.
- 分子量
-
Predicted: 66 kDa
Observed: 6 kDa - 基因ID
- 80149
- NCBI登录号
- NP_079355
- UniProt
- Q5D1E8
- 途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of fat Cell Differentiation
-
