At least two isoforms of IRF2BP2 are known to exist, this antibody will detect both.
纯化方法
IRF2BP2 Antibody is affinity chromatography purified via peptide column.
免疫原
IRF2BP2 antibody was raised against an 17 amino acid synthetic peptide near the amino terminus of human IRF2BP2. The immunogen is located within amino acids 150 - 200 of IRF2BP2.
IRF2BP2
适用: 人
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
Cy5.5
应用备注
IRF2BP2 antibody can be used for detection of IRF2BP2 by immunohistochemistry at 5 μ,g/mL.
Antibody validated: Immunohistochemistry in human samples. All other applications and species not yet tested.
限制
仅限研究用
状态
Liquid
浓度
1 mg/mL
缓冲液
IRF2BP2 Antibody is supplied in PBS containing 0.02 % sodium azide.
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C,4 °C
储存方法
IRF2BP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
抗原
IRF2BP2
(Interferon Regulatory Factor 2 Binding Protein 2 (IRF2BP2))
IRF2BP2 Antibody: IRF2BP2, like the related protein IRF2BP1, is a co-repressor that interacts specifically with the C-terminal repression domain of Interferon Regulatory Factor 2 (IRF2). IRF2BP2 is a direct target gene of p53 and is involved in cell survival during the p53 stress response, able to impede the p53-mediated transactivation of p21 and Bax. IRF2BP2 is also a co-factor of VGLL4 and is required to induce the expression of vascular endothelial growth factor A (VEGF-A) in muscle. It is normally found in the nucleus of skeletal muscle and cardiac cells, but can be found in the cytoplasm during skeletal muscle differentiation.