PLEKHM3 抗体 (C-Term)
PLEKHM3
适用: 人, 小鼠, 大鼠
WB, ELISA, IHC (p), IF
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all PLEKHM3 products
- PLEKHM3 (Pleckstrin Homology Domain Containing, Family M, Member 3 (PLEKHM3))
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抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PLEKHM3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- PLEKHM3 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- PLEKHM3 antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human PLEKHM3. The immunogen is located within the last 50 amino acids of PLEKHM3.
- 亚型
- IgG
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- 应用备注
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PLEKHM3 antibody can be used for detection of PLEKHM3 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PLEKHM3 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- PLEKHM3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- PLEKHM3 (Pleckstrin Homology Domain Containing, Family M, Member 3 (PLEKHM3))
- 别名
- PLEKHM3 (PLEKHM3 产品)
- 别名
- PLEKHM1L antibody, DAPR antibody, 9430067K14Rik antibody, A230102O09Rik antibody, AI449570 antibody, Plekhm1l antibody, Dapr antibody, RGD1307151 antibody, pleckstrin homology domain containing, family M, member 3 antibody, pleckstrin homology domain containing M3 antibody, pleckstrin homology domain containing M3 L homeolog antibody, PLEKHM3 antibody, Plekhm3 antibody, plekhm3.L antibody
- 背景
- PLEKHM3 Antibody: PLEKHM3, also known as DAPR, is a member of the M family of Pleckstrin homology domain-containing proteins. PLEKHM3 was initially identified through chromatin immunoprecipitation and CpG microarray analysis examining proteins regulated by myocyte-enhancing factor 2. In C2C12 myoblast cells, PLEKHM3 binds to the PI3K signaling member protein kinase B in the cytosol prior to differentiation into myotubes. Following the initiation of differentiation, PLEKHM3 was also found in membrane fractions. Knockdown of PLEKHM3 expression by RNAi resulted in the inhibition of myotube formation, suggesting that PLEKHM3 is a key component required by myoblasts for orchestrating their differentiation during myogenesis.
- 基因ID
- 389072
- UniProt
- Q6ZWE6
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