Hax1b (N-Term) 抗体
适用: 人, 小鼠, 大鼠
ELISA, WB
宿主: 兔
Polyclonal
unconjugated
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- 抗原
- Hax1b
- 抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆类型
- 多克隆
- 应用范围
- ELISA, Western Blotting (WB)
- 特异性
- At least four isoforms of Hax1 are known to exist. This antibody is predicted to recognize Hax1b.
- 纯化方法
- Hax1b Antibody is affinity chromatography purified via peptide column.
- 免疫原
- Hax1b antibody was raised against a 10 amino acid synthetic peptide near the amino terminus of human Hax1b. The immunogen is located within the first 50 amino acids of Hax1b.
- 亚型
- IgG
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- 应用备注
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Hax1b antibody can be used for detection of Hax1b by Western blot at 1 - 2 μ,g/mL.
Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Hax1b Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- Hax1b antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- Hax1b
- 背景
- Hax1b Antibody: The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons when cytokines are limiting.
- 基因ID
- 10456
- NCBI登录号
- NP_001018238
- UniProt
- O00165
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