TARDBP 抗体 (AA 160-210)
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北京 101111
Quick Overview for TARDBP 抗体 (AA 160-210) (ABIN6990776)
抗原
See all TARDBP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 160-210
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特异性
- At least two isoforms are known to exist for this protein, this TDP43 antibody only recongizes the longer of the two isoforms.
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纯化方法
- TDP43 Antibody is affinity chromatography purified via peptide column.
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免疫原
- TDP43 antibody was raised against a 18 amino acid synthetic peptide from near the center of human TDP43. The immunogen is located within amino acids 160 - 210 of TDP43.
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亚型
- IgG
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anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibody
TARDBP 适用: 人 WB, IF, ELISA, IP, IHC (p), RNAi 宿主: 小鼠 Monoclonal 2E2-D3 unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 104-262) antibodyTARDBP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 1-260) antibodyTARDBP 适用: 人 WB, IP, RIP 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyTARDBP 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyTARDBP 适用: 人 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6G2D8 unconjugated
anti-TAR DNA Binding Protein (TARDBP) (C-Term) antibodyTARDBP 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 1-100) antibodyTARDBP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) antibodyKO Validated TARDBP 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (N-Term) antibodyTARDBP 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TAR DNA Binding Protein (TARDBP) (AA 1-396) antibodyTARDBP 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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TDP43 antibody can be used for detection of TDP43 by Western blot at 0.5 - 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- TDP43 Antibody is supplied in PBS containing 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,4 °C
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储存方法
- TDP43 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- TARDBP (TAR DNA Binding Protein (TARDBP))
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别名
- TDP43
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背景
- TDP43 Antibody: TDP43 was initially identified as a novel cellular protein that bound to HIV-1 virus TAR DNA sequence motifs and acts a transcriptional repressor to the HIV-1 LTR. Later experiments revealed that TDP43 also regulates the splicing of exon 9 of the cystic fibrosis transmembrane conductance regular (CFTR), most likely through the association with the UG repeats at the 3'splice site. A hyperphosphorylated, ubiquitinated, and cleaved form of TDP43 known as pathologic TDP43 is the major disease protein in ubiquitin-positive, tau-, and alpha-synuclein-negative frontotemporal dementia (FLTD-U). TDP43 is not related to TRBP1, and RNA binding protein that binds HIV-1 TAR RNA sequences.
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分子量
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Predicted: 46 kDa
Observed: 46 kDa -
基因ID
- 23435
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UniProt
- Q13148
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
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