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SUMO 抗体 (N-Term)

适用: 人, 大鼠, 小鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990687
发货至: 中国
  • 抗原 See all SUMO products
    SUMO
    抗原表位
    • 7
    • 2
    • 1
    • 1
    • 1
    N-Term
    适用
    • 15
    • 9
    • 4
    • 1
    人, 大鼠, 小鼠
    宿主
    • 18
    • 2
    克隆类型
    • 18
    • 2
    多克隆
    标记
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    This SUMO antibody is un-conjugated
    应用范围
    • 19
    • 19
    • 9
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Sumo Antibody is affinity chromatography purified via peptide column.
    免疫原
    Sumo antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human sumo. The immunogen is located within the first 50 amino acids of Sumo.
    亚型
    IgG
  • 应用备注
    Sumo antibody can be used for detection of sumo by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Sumo Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    Sumo antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    SUMO
    Abstract
    SUMO 产品
    别名
    CG4494 antibody, Dm0342 antibody, DmSUMO-1 antibody, DmSmt3 antibody, Dmel\\CG4494 antibody, Dmsmt3 antibody, SMT3 antibody, SUMO antibody, Smt3 antibody, Sumo antibody, anon-EST:Posey240 antibody, dSmt3 antibody, dsmt3 antibody, l(2)04493 antibody, l(2)SH0182 antibody, l(2)SH2 0182 antibody, sumo antibody, CG4494 gene product from transcript CG4494-RA antibody, smt3 antibody
    背景
    Sumo Antibody: The sumo family of proteins is related both structurally and functionally to ubiquitin in that they are post-translationally attached to the e-amino group of a lysine residue of the substrate protein. This sumoylation plays a number of roles in DNA replication and repair, protein targeting to various subnuclear structures, and the regulation of numerous cellular processes including the inflammatory response in mammalian cells. Sumo was initially identified as a covalent modification of RanGAP1 in studies on nuclear import in mammalian cells. More recently, sumo has been shown to be involved in the regulation of transcription factors, possibly by enhancing their interactions with co-repressors. Sumo is also thought to play some role in the modulation of ubiquitin-mediated degradation of proteins by acting as an inhibitor. At least four different isoforms of sumo are known to exist, Sumo antibody will only recognize isoform 1.
    基因ID
    7341
    UniProt
    P63165
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