PAK2 抗体 (N-Term)
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- 抗原 See all PAK2 抗体
- PAK2 (P21-Activated Kinase 2 (PAK2))
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抗原表位
- AA 20-70, N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PAK2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- PAK2 Antibody is affinity chromatography purified via peptide column.
- 免疫原
- Anti-PAK2 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human PAK2. The immunogen is located within amino acids 20-70 of PAK2.
- 亚型
- IgG
- Top Product
- Discover our top product PAK2 Primary Antibody
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anti-P21-Activated Kinase 2 (PAK2) (AA 131-230) antibody
PAK2 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1E1 unconjugated
anti-P21-Activated Kinase 2 (PAK2) antibodyPAK2 适用: 人, 猴 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 3B5 unconjugated
anti-P21-Activated Kinase 2 (PAK2) (AA 1-212) antibodyPAK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 2 (PAK2) antibodyPAK2 适用: 人 WB, ELISA, IP, FACS 宿主: 兔 Monoclonal 6D12 unconjugated Recombinant Antibody
anti-P21-Activated Kinase 2 (PAK2) (AA 177-419) antibodyPAK2 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 2 (PAK2) (pThr402) antibodyPAK2 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 2 (PAK2) (AA 192-222) antibodyPAK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 2 (PAK2) (N-Term) antibodyPAK2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 2 (PAK2) (pSer20) antibodyPAK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-P21-Activated Kinase 2 (PAK2) (Ser62) antibodyPAK2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: 0.5-2 μ,g/mL, IHC: 10 μ,g/mL, IF: 20 μ,g/mL.
Antibody validated: Western Blot in human, mouse and rat samples, Immunohistochemistry and Immunofluorescence in mouse samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PAK2 Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- PAK2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- PAK2 (P21-Activated Kinase 2 (PAK2))
- 别名
- PAK2 (PAK2 产品)
- 别名
- PAK65 antibody, PAKgamma antibody, gamma-PAK antibody, 5330420P17Rik antibody, A130002K10Rik antibody, AI836325 antibody, D16Ertd269e antibody, PAK-2 antibody, mKIAA4182 antibody, pak2 antibody, cb422 antibody, kinase antibody, zgc:91798 antibody, wu:fb71h01 antibody, si:dz198m22.1 antibody, pak65 antibody, pakgamma antibody, PAKI antibody, Pak3 antibody, CH73-159L23.1 antibody, wu:fc52b03 antibody, zgc:113857 antibody, p21 (RAC1) activated kinase 2 antibody, p21 protein (Cdc42/Rac)-activated kinase 2 antibody, p21 protein (Cdc42/Rac)-activated kinase 2a antibody, p21 protein (Cdc42/Rac)-activated kinase 2 S homeolog antibody, p21 protein (Cdc42/Rac)-activated kinase 2b antibody, PAK2 antibody, Pak2 antibody, pak2a antibody, pak2.S antibody, pak2b antibody
- 背景
- PAK2 Antibody: The p21-activated kinases (PAKs) are serine-threonine kinases that bind to the active forms of Cdc42 and Rac. They are divided into two groups, the first of which include PAK1, 2 and 3, and can be activated by Cdc42/Rac binding. Group 1 PAKs contain an autoinhibitory domain whose activity is regulated by Cdc42/Rac binding. The group 1 PAKs are known to be involved in cellular processes such as gene transcription, apoptosis, and cell morphology and motility. Much less is known about the second group, which includes PAK4, 5 and 6, and are not activated by Cdc42/Rac binding. Of the six PAK proteins, only PAK2 is ubiquitously expressed and cleaved by caspase-3. This cleavage removes the amino-terminal regulatory domain and generates a constitutively active kinase fragment. Recent experiments have shown that following cleavage, the active fragment is myristoylated and directed to the plasma membrane and membrane ruffles where it promotes cell death via increased signaling through the c-Jun N-terminal kinase pathway, but without compromising mitochondrial integrity.
- 分子量
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Predicted: 58kD
Observed: 58 kD kDa - 基因ID
- 5062
- NCBI登录号
- NP_002568
- UniProt
- Q13177
- 途径
- MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
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