TANK 抗体 (C-Term)
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- 抗原 See all TANK 抗体
- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
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抗原表位
- AA 350-400, C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TANK antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- TANK Antibody is affinity chromatography purified via peptide column.
- 免疫原
- TANK antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human TANK. The immunogen is located within amino acids 350 - 400 of TANK.
- 亚型
- IgG
- Top Product
- Discover our top product TANK Primary Antibody
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anti-TRAF Family Member-Associated NFKB Activator (TANK) (AA 131-369) antibody
TANK 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-TRAF Family Member-Associated NFKB Activator (TANK) (AA 4-98) antibodyTANK 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TRAF Family Member-Associated NFKB Activator (TANK) (Internal Region) antibodyTANK 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TRAF Family Member-Associated NFKB Activator (TANK) (AA 1-119) antibodyTANK 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TRAF Family Member-Associated NFKB Activator (TANK) (AA 88-114) antibodyTANK 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22057 unconjugated
anti-TRAF Family Member-Associated NFKB Activator (TANK) (Center) antibodyTANK 适用: 人, 小鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-TRAF Family Member-Associated NFKB Activator (TANK) (C-Term) antibodyTANK 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-TRAF Family Member-Associated NFKB Activator (TANK) (N-Term) antibodyTANK 适用: 人, 兔, Cow, 马, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-TRAF Family Member-Associated NFKB Activator (TANK) (N-Term) antibodyTANK 适用: 人, 小鼠, 大鼠, 兔, Cow, 马, 犬, 豚鼠, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TRAF Family Member-Associated NFKB Activator (TANK) (N-Term) antibodyTANK 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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TANK antibody can be used for the detection of TANK by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples and Immunofluorescence in rat samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- TANK Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- TANK antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
- 别名
- TANK (TANK 产品)
- 别名
- I-TRAF antibody, ITRAF antibody, TRAF2 antibody, C86182 antibody, E430026L09Rik antibody, zgc:153048 antibody, i-traf antibody, tank antibody, traf2 antibody, TRAF family member associated NFKB activator antibody, TRAF family member-associated Nf-kappa B activator antibody, TRAF family member-associated NFKB activator antibody, TRAF family member associated NFKB activator L homeolog antibody, TANK antibody, Tank antibody, tank antibody, tank.L antibody
- 背景
- TANK Antibody: TANK was initially identified as a novel TRAF-interacting protein that regulated TRAF-mediated signal transduction. Specifically, ligand binding by surface receptors in the tumor necrosis factor (TNF) receptor and Toll/interleukin-1 (IL-1) receptor families lead to the formation of a TRAF/TANK complex that mediates the activation of the transcription factor NF-κ,B. This activation of NF-κ,B occurs through an association with the kinases IKKε, and TBK1. More recently, it was shown that these proteins can then form a complex with NEMO, a protein that regulates the activity of the Iκ,B complex. This suggests that in addition to the possibility that TBK1 and IKKε, activate the IKKs, the association with the IKK complex may help these kinases modulate other functions, such as the transactivation potential of NF-κ,B proteins. At least two isoforms of TANK are known to exist.
- 分子量
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Predicted: 47 kDa
Observed: 50 kDa - 基因ID
- 10010
- NCBI登录号
- NP_004171
- UniProt
- Q92844
- 途径
- p53 Pathway, TLR signaling, Activation of Innate immune Response
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