AIM (AA 60-110), (N-Term) 抗体
适用: 人, 小鼠
ELISA, WB, IHC (p), IF
宿主: 兔
Polyclonal
unconjugated
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- 抗原
- AIM
- 抗原表位
- AA 60-110, N-Term
- 适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
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标记
- 非结合性
- 应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- AIM Antibody is affinity chromatography purified via peptide column.
- 免疫原
- AIM antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human AIM. The immunogen is located within amino acids 60 - 110 of AIM.
- 亚型
- IgG
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- 应用备注
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AIM antibody can be used for the detection of AIM by Western blot at 1 - 4 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- AIM Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- AIM antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- AIM
- 别名
- 5830438K24Rik antibody, AI452015 antibody, AIM antibody, VEA antibody, BL-AC/P26 antibody, CLEC2C antibody, EA1 antibody, GP32/28 antibody, MLR-3 antibody, CD69 antigen antibody, CD69 molecule antibody, Cd69 antibody, CD69 antibody
- 背景
- AIM Antibody: Apoptosis inhibitor of macrophages (AIM) is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that AIM functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. AIM was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant AIM significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that AIM functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection.
- 基因ID
- 922
- UniProt
- O43866
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