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TRAF2 抗体 (C-Term)

This anti-TRAF2 antibody is a 兔 多克隆 antibody detecting TRAF2 in WB, ELISA, IP 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6990594
发货至: 中国

Quick Overview for TRAF2 抗体 (C-Term) (ABIN6990594)

抗原

See all TRAF2 抗体
TRAF2 (TNF Receptor-Associated Factor 2 (TRAF2))

适用

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人, 小鼠, 大鼠

宿主

  • 74
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克隆类型

  • 65
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多克隆

标记

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This TRAF2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    纯化方法

    TRAF2 Antibody is affinity chromatography purified via peptide column.

    免疫原

    TRAF2 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human TRAF2. The immunogen is located within the last 50 amino acids of TRAF2.

    亚型

    IgG
  • 应用备注

    TRAF2 antibody can be used for the detection of TRAF2 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL.

    Antibody validated: Western Blot in mouse samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    TRAF2 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    TRAF2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    TRAF2 (TNF Receptor-Associated Factor 2 (TRAF2))

    别名

    TRAF2

    背景

    TRAF2 Antibody: Tumor necrosis factor (TNF) receptor associated factors (TRAFs) were initially discovered as adaptor proteins that link the TNF receptor superfamily to signaling pathways and are thus important regulators of cell death and cellular response to stress. TRAF proteins share a homology region that allows them to bind to cell receptors and other TRAF proteins, causing the activation of different signal cascades depending on the TRAFs involved. For example, TRAF2 and TRAF3 directly bind to the CD40, a TNF receptor superfamily member involved in inducing B cell immunity, and are critical for NF-κ,B activation in mouse B lymphocytes. TRAF2 along with TRAF6 has also been shown to be required for CD40 signaling in nonhemopoietic cells. TRAF2 also interacts with the TRFR superfamily member lymphotoxin-beta receptor (LTbetaR) in association with TRAF3 and the apoptosis inhibitors cIAP1 and Smac.

    分子量

    Observed: 53 kDa

    基因ID

    7186

    UniProt

    Q12933

    途径

    NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded Protein Response, S100 Proteins
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