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IRF7 抗体 (AA 200-230)

IRF7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990585
发货至: 中国
  • 抗原 See all IRF7 抗体
    IRF7 (Interferon Regulatory Factor 7 (IRF7))
    抗原表位
    • 17
    • 17
    • 15
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 200-230
    适用
    • 67
    • 54
    • 53
    • 17
    • 8
    • 3
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 66
    • 2
    克隆类型
    • 57
    • 11
    多克隆
    标记
    • 21
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This IRF7 antibody is un-conjugated
    应用范围
    • 47
    • 17
    • 14
    • 14
    • 13
    • 12
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    Several isoforms of IRF7 are known to exist.
    纯化方法
    IRF7 Antibody is affinity chromatography purified via peptide column.
    免疫原
    Anti-IRF7 antibody was raised against a peptide corresponding to 17 amino acids near the center of human IRF7. The immunogen is located within amino acids 200-230 of IRF7.
    亚型
    IgG
    Top Product
    Discover our top product IRF7 Primary Antibody
  • 应用备注
    WB: 0.5-1 μ,g/mL, IF: 20 μ,g/mL, IHC: 2-5 μ,g/mL.

    Antibody validated: Western Blot in human, mouse and rat samples. Immunofluorescence in mouse samples. Immunohistochemistry in human, mouse and rat samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    IRF7 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    IRF7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    IRF7 (Interferon Regulatory Factor 7 (IRF7))
    别名
    IRF7 (IRF7 产品)
    别名
    wu:fl24c03 antibody, zgc:66043 antibody, zgc:77947 antibody, IRF7 antibody, irf7 antibody, IRF-7H antibody, IRF7A antibody, IRF7B antibody, IRF7C antibody, IRF7H antibody, interferon regulatory factor 7 antibody, irf7 antibody, IRF7 antibody, Irf7 antibody
    背景
    IRF7 Antibody: Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-alpha/beta genes. IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF7 play a major role in the innate immune pathway, interacting with the Toll-like receptor (TLR) adaptor proteins MyD88 and Tirp/TRAM and functioning as an intermediate TLR4 and TLR9 signaling. There are at least four differentially spliced isoforms of IRF7, although their function has not been clearly established.
    基因ID
    3665
    UniProt
    Q92985
    途径
    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Autophagy
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