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TRAF3 抗体 (N-Term)

This anti-TRAF3 antibody is a 兔 多克隆 antibody detecting TRAF3 in WB, ELISA 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6990568
发货至: 中国

Quick Overview for TRAF3 抗体 (N-Term) (ABIN6990568)

抗原

See all TRAF3 抗体
TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This TRAF3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
  • 抗原表位

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    AA 20-70, N-Term

    纯化方法

    TRAF3 Antibody is affinity chromatography purified via peptide column.

    免疫原

    TRAF3 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human. The immunogen is located within amino acids 20 - 70 of TRAF3.

    亚型

    IgG
  • 应用备注

    TRAF3 antibody can be used for the detection of TRAF3 by Western blot at 2 - 4 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL.

    Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    TRAF3 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    TRAF3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

    别名

    TRAF3

    背景

    TRAF3 Antibody: Tumor necrosis factor (TNF) receptor associated factors (TRAFs) are the major signal transducers for the TNF receptor superfamily and the interleukin-1 receptor/Toll-like receptor (IL-1/TLR) superfamily. TRAF3 was first identified by its interaction with CD40 and the Epstein-Barr virus transforming protein LMP1. Several TRAF3 mRNA splice variants exist and some of these can activate the transcription factor NF-κ,B. Besides CD40, TRAF3 also interacts with the TRFR superfamily member lymphotoxin-beta receptor (LTbetaR) in association with TRAF2 and the apoptosis inhibitors cIAP1 and Smac. It has been suggested that TRAF3 induces mitochondria-mediated apoptosis upon binding of the TNF family cytokine LIGHT by LTbetaR.

    基因ID

    7187

    NCBI登录号

    NP_663777

    UniProt

    Q13114

    途径

    NF-kappaB Signaling, Apoptosis, TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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