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Bcl-2 抗体 (AA 80-130)

BCL2 适用: 人, 小鼠 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6990471
发货至: 中国
  • 抗原 See all Bcl-2 (BCL2) 抗体
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    抗原表位
    • 48
    • 34
    • 23
    • 22
    • 21
    • 18
    • 16
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    AA 80-130
    适用
    • 406
    • 165
    • 157
    • 34
    • 23
    • 22
    • 16
    • 9
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 325
    • 104
    • 5
    • 2
    • 1
    克隆类型
    • 324
    • 112
    多克隆
    标记
    • 197
    • 31
    • 30
    • 23
    • 22
    • 14
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
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    • 2
    • 2
    • 1
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    This Bcl-2 antibody is un-conjugated
    应用范围
    • 351
    • 174
    • 157
    • 110
    • 97
    • 95
    • 80
    • 61
    • 56
    • 27
    • 23
    • 22
    • 18
    • 8
    • 8
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    纯化方法
    Bcl-2 Antibody is Ion exchange chromatography purified.
    免疫原
    Anti-Bcl-2 antibody was raised against a peptide corresponding to 14 amino acids near the center of human Bcl-2. The immunogen is located within amino acids 80-130 of Bcl-2.
    亚型
    IgG
    Top Product
    Discover our top product BCL2 Primary Antibody
  • 应用备注
    WB: 1-4μ,g/mL, ICC: 2 μ,g/mL.

    Antibody validated: Western Blot in human and mouse samples, Immunocytochemistry in mouse samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Bcl-2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    Bcl-2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
    别名
    Bcl-2 (BCL2 产品)
    别名
    Bcl-2 antibody, PPP1R50 antibody, bcl-2 antibody, AW986256 antibody, C430015F12Rik antibody, D630044D05Rik antibody, D830018M01Rik antibody, BCL-2 antibody, Bcl2 antibody, BCL2, apoptosis regulator antibody, B cell leukemia/lymphoma 2 antibody, B-cell CLL/lymphoma 2a antibody, B-cell CLL/lymphoma 2 protein antibody, BCL2 antibody, Bcl2 antibody, bcl2a antibody, BCL-2 antibody
    背景
    Bcl-2 Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Bcl-2 is the founding member of a family of over 20 proteins that are critical regulators of apoptosis. These can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bcl-2 is an inner mitochondrial membrane protein that inhibits apoptosis. It is thought to act by interacting with pro-apoptotic Bcl-2 family members such as Bak and Bad. Overexpression of Bcl-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.
    分子量
    Predicted: 26kD

    Observed: 26 kD kDa
    基因ID
    596
    UniProt
    P10415
    途径
    MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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