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TLR8 抗体 (AA 790-840)

This anti-TLR8 antibody is a 兔 多克隆 antibody detecting TLR8 in WB, ELISA, ICC 和 IF. Suitable for 人 和 小鼠.
产品编号 ABIN6990456
发货至: 中国

Quick Overview for TLR8 抗体 (AA 790-840) (ABIN6990456)

抗原

See all TLR8 抗体
TLR8 (Toll-Like Receptor 8 (TLR8))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This TLR8 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

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    AA 790-840

    纯化方法

    TLR8 Antibody is affinity chromatography purified via peptide column.

    免疫原

    TLR8 antibody was raised against a peptide corresponding to 16 amino acids near the middle of human TLR8. The immunogen is located within amino acids 790 - 840 of TLR8.

    亚型

    IgG
  • 应用备注

    TLR8 antibody can be used for detection of TLR8 by Western blot at 0.5 to 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    TLR8 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    TLR8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    TLR8 (Toll-Like Receptor 8 (TLR8))

    别名

    TLR8

    背景

    TLR8 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848.

    分子量

    Predicted: 112 kDa

    Observed: 107 kDa

    基因ID

    51311

    NCBI登录号

    NP_619542

    UniProt

    Q9NR97

    途径

    TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
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