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KAP1 抗体 (C-Term)

This anti-KAP1 antibody is a 兔 多克隆 antibody detecting KAP1 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6990391
发货至: 中国

Quick Overview for KAP1 抗体 (C-Term) (ABIN6990391)

抗原

See all KAP1 (TRIM28) 抗体
KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

适用

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人, 小鼠, 大鼠

宿主

  • 114
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克隆类型

  • 107
  • 28
多克隆

标记

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This KAP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    C-Term

    特异性

    At least three isoforms of TRIM28 are known to exist, this antibody will detect all three isoforms

    纯化方法

    TRIM28 Antibody is affinity chromatography purified via peptide column.

    免疫原

    Rabbit polyclonal TRIM28 antibody was raised against a 14 amino acid peptide near the carboxy terminus of human TRIM28. The immunogen is located within the last 50 amino acids of TRIM28.

    亚型

    IgG
  • 应用备注

    TRIM28 antibody can be used for detection of TRIM28 by Western blot at 1 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    TRIM28 Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    TRIM28 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原

    KAP1 (TRIM28) (Tripartite Motif Containing 28 (TRIM28))

    别名

    TRIM28

    背景

    TRIM28 Antibody: TRIM28, also known as KAP-1, is a member of the Transcriptional Intermediary Factor 1 (TIF1) subfamily and contains a RING finger, B box, Coiled coil, PHD/TTC, and bromodomain. TRIM28 is a corepressor for Kruppel-associated box (KRAB)-domain-containing zinc finger proteins and plays a critical role in early embryogenesis. TRIM28 acts as a transcriptional mediator by binding liganded nuclear receptors, including retinoic acid (RAR), retinoid X (RXR) and estrogen (ER) receptors. TRIM28 associates with both heterochromatin and euchromatin, causing gene silencing by both HP1 binding and histone deacetylation.

    分子量

    Predicted: 92 kDa

    基因ID

    10155

    NCBI登录号

    NP_005753

    UniProt

    Q13263

    途径

    Hedgehog Signaling, Positive Regulation of Response to DNA Damage Stimulus
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